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depopulate
/diˈpɑːpjəˌleɪt/
US
UK
verb
-lates; -lated; -lating
[+ obj] :to greatly reduce the number of people living in (a city, region, etc.)
Large
areas
of
the
country
had
been
depopulated
by
disease
.
an
empty
,
depopulated
landscape
US